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Vitamin D Role in cancer prevention and recovery

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Vitamin D Role in cancer prevention and recovery

Postby Admin » 30 Jun 13 01:01

The vitamin D hormone, calcitriol, has been found to induce death of cancer cells in vitro and in vivo. The anti-cancer activity of vitamin D is thought to result from its role as a nuclear transcription factor that regulates cell growth, differentiation, apoptosis and a wide range of cellular mechanisms central to the development of cancer. These effects may be mediated through vitamin D receptors expressed in cancer cells.A search of primary and review medical literature published between 1970 and 2007 found an increasing body of research supporting the hypothesis that the active form of vitamin D has significant, protective effects against the development of cancer. Epid vitamin D and risk of developing and/or surviving cancer. In 2005, scientists released a metastudy which demonstrated a beneficial correlation between vitamin D intake and prevention of cancer. Drawing from a meta-analysis of 63 published reports, the authors showed that inemiological studies show an inverse association between sun exposure, serum levels of 25(OH)D, and intakes oftake of an additional 1,000 international units (IU) (or 25 micrograms) of vitamin D daily reduced an individual's colon cancer risk by 50%, and breast and ovarian cancer risks by 30%. A scientific review undertaken by the National Cancer Institute found that vitamin D was beneficial in preventing colorectal cancer, which showed an inverse relationship with blood levels of 80 nmol/L or higher associated with a 72% risk reduction. See below this figure is believed to be 77%.
update:28/10/2009
A 2006 study using data on over 4 million cancer patients from 13 different countries showed a marked difference in cancer risk between countries classified as sunny and countries classified as less–sunny for a number of different cancers.Research has also suggested that cancer patients who have surgery or treatment in the summer and therefore make more endogenous vitamin D have a better chance of surviving their cancer than those who undergo treatment in the winter when they are exposed to less sunlight. Another 2006 study found that taking the U.S. RDA of vitamin D (400 IU per day) cut the risk of pancreatic cancer by 43% in a sample of more than 120,000 people from two long-term health surveys. A randomized intervention study involving 1,200 women, published in June 2007, reports that vitamin D supplementation (1,100 international units (IU)/day) resulted in a 60% reduction in cancer incidence, during a four-year clinical trial, rising to a 77% reduction for cancers diagnosed after the first year (and therefore excluding those cancers more likely to have originated prior to the vitamin D intervention). Research has also indicated beneficial effects of high levels of calcitriol on patients with advanced prostate cancer.Low levels of vitamin D in serum have also been correlated with breast cancer disease progression and bone metastases, and studies suggest that increased intake of vitamin D reduces the risk of breast cancer in premenopausal women. Polymorphisms of the vitamin D receptor (VDR) gene have been associated with an increased risk of breast cancer.Impairment of the VDR-mediated gene expression is thought to alter mammary gland development or function and may predispose cells to malignant transformation. Women with homozygous FOK1 mutations in the VDR gene had an increased risk of breast cancer compared with the women who did not. FOK1 mutation has also been associated with decreasing bone mineral density which in turn may be associated with an increase in the risk of breast cancer.
Sunshine and Your Health
If well adults and adolescents regularly avoid sunlight exposure, research indicates a necessity to supplement with at least 5,000 units (IU) of vitamin D daily. To obtain this amount from milk one would need to consume 50 glasses. With a multivitamin more than 10 tablets would be necessary. Neither is advisable.
The skin produces approximately 10,000 IU vitamin D in response 20–30 minutes summer sun exposure—50 times more than the US government's recommendation of 200 IU per day!
How To Get Enough Vitamin D
There are 3 ways for adults to insure adequate levels of vitamin D:
· regularly receive midday sun exposure in the late spring, summer, and early fall, exposing as much of the skin as possible.
· regularly use a sun bed (avoiding sunburn) during the colder months.
· take 5,000 IU per day for three months, then obtain a 25-hydroxyvitamin D test. Adjust your dosage so that blood levels are between 50–80 ng/mL (or 125–200 nM/L) year-round.

Anyone wanting to know more on this subject can inbox stan with any questions or request a tel call back.Its free so why not ask and leave no stone unturned in the quest to save a friend or a member of your family or yourself.
Can also offer free sunbed sessions and a cancer fighting diet way more powerful than chemo with no side effects. You are welcome to inbox me for help in confidence.
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